Description

2,2,2-Trifluoro-1-(3-Fluorophenyl)Ethylaminehydrochloride is a high-purity fluorinated amine hydrochloride salt, a critical building block in advanced organic synthesis. This compound is valued for its role in introducing the trifluoroethylamine pharmacophore, which can significantly alter the metabolic stability, lipophilicity, and binding affinity of target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential CNS agents and crop protection chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in neuroscience and oncology research.
• Agrochemical Synthesis: Used in creating advanced herbicides and pesticides where fluorine atoms enhance biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals that require fluorinated aromatic amine components.
• Chemical Biology & Proteomics: Employed in the design of activity-based probes and affinity tags to study enzyme function and protein interactions.
• PET Radiopharmaceuticals: Potential precursor for fluorine-18 labeled tracers used in positron emission tomography (PET) imaging.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client R&D programs.

Basic Information

Product Name	2,2,2-Trifluoro-1-(3-Fluorophenyl)Ethylaminehydrochloride
CAS No.	1185302-13-9
Molecular Formula	C8H8ClF4N
Molecular Weight	229.60 g/mol
Synonyms	1-(3-Fluorophenyl)-2,2,2-trifluoroethanamine hydrochloride; α-(Trifluoromethyl)-3-fluorobenzeneethanamine hydrochloride; 3-Fluoro-α-(trifluoromethyl)benzeneethanamine hydrochloride; 2,2,2-Trifluoro-1-(3-fluorophenyl)ethan-1-amine hydrochloride; 3-Fluoro-α-(trifluoromethyl)phenethylamine hydrochloride; (3-Fluorophenyl)(trifluoromethyl)methylamine hydrochloride; 1-(3-Fluorophenyl)-2,2,2-trifluoroethylamine HCl
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(3-Fluorophenyl)Ethylaminehydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.