Description

2-(2-Aminoethyl)Quinazolin-4(3H)-One Hydrochloride is a high-purity, pharmaceutically relevant organic salt. This compound serves as a critical building block in medicinal chemistry, particularly for the synthesis of novel drug candidates targeting various therapeutic areas. It is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of quinazoline-based active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel quinazoline-derived drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for various biological targets.
• Kinase Inhibitor Synthesis: Serves as a core scaffold in the preparation of potential kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A starting material for the custom synthesis of complex molecules under cGMP or research-grade conditions.
• Academic & Institutional Research: Supports fundamental research in heterocyclic chemistry and drug discovery programs.

Basic Information

Product Name	2-(2-Aminoethyl)Quinazolin-4(3H)-One Hydrochloride
CAS No.	1185298-40-1
Molecular Formula	C₁₀H₁₂N₃O•HCl
Molecular Weight	225.68 g/mol (free base: 190.22 g/mol)
Synonyms	2-(2-Aminoethyl)-4(3H)-quinazolinone hydrochloride; 2-(2-Aminoethyl)-3,4-dihydro-4-oxoquinazoline hydrochloride; 4(3H)-Quinazolinone, 2-(2-aminoethyl)-, hydrochloride; 2-(2-Aminoethyl)quinazolin-4-ol hydrochloride; Quinazolin-4(3H)-one, 2-(2-aminoethyl)-, hydrochloride; 1185298-40-1; CAS 1185298-40-1
EINECS	Contact for details

Quality Control

Our 2-(2-Aminoethyl)Quinazolin-4(3H)-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability, consistency, and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.