Description

3,3'-Difluoro[1,1'-Biphenyl]-4-Ylaminehydrochloride is a high-purity, advanced pharmaceutical intermediate and organic building block. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry and materials science, where its biphenyl core and fluorine substituents offer valuable structural and electronic properties. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the stability imparted by the fluorine atoms.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and transition metal complexes.
• Organic Electronic Materials: A potential monomer or dopant in the development of organic light-emitting diodes (OLEDs) and semiconductors due to its conjugated biphenyl system.
• Life Sciences Research: Employed in biochemical research as a probe or tag molecule for studying biological interactions and pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity fluorinated biphenyl derivatives.

Basic Information

Product Name	3,3'-Difluoro[1,1'-Biphenyl]-4-Ylaminehydrochloride
CAS No.	1185296-90-5
Molecular Formula	C12H10ClF2N
Molecular Weight	241.66 g/mol
Synonyms	4-Amino-3,3'-difluorobiphenyl Hydrochloride; 3,3'-Difluoro-4-aminobiphenyl Hydrochloride; 3,3'-Difluorobiphenyl-4-amine Hydrochloride; [1,1'-Biphenyl]-4-amine, 3,3'-difluoro-, hydrochloride; 4-Amino-3,3'-difluoro-1,1'-biphenyl Hydrochloride; 3,3'-DFBP-4-Amine HCl
EINECS	Contact for details

Quality Control

Our 3,3'-Difluoro[1,1'-Biphenyl]-4-Ylaminehydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.