Description

4-(4,6-Dimethyl-2-Oxo-2H-Pyrimidin-1-Yl)-Butyric Acid Hydrochloride CAS NO 1185293-26-8 is a high-purity, non-nucleoside pyrimidine derivative used as a critical pharmaceutical intermediate. Its value lies in its role as a versatile building block for synthesizing more complex active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in antiviral and anticancer research.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the production route for complex APIs that incorporate a functionalized pyrimidine core.
• Biochemical Research: Serves as a precursor or reference standard in biochemical assays and proteomics studies.
• Agrochemical Development: Employed in the research and synthesis of new crop protection agents and herbicides.
• Fine Chemical Production: Utilized in custom synthesis and the manufacture of specialty chemicals for various industrial applications.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new chemical entities and reaction pathways.

Basic Information

Product Name	4-(4,6-Dimethyl-2-Oxo-2H-Pyrimidin-1-Yl)-Butyric Acid Hydrochloride
CAS No.	1185293-26-8
Molecular Formula	C₁₀H₁₅ClN₂O₃
Molecular Weight	246.69 g/mol
Synonyms	1-(3-Carboxypropyl)-4,6-dimethyl-2(1H)-pyrimidinone hydrochloride; 4-(4,6-Dimethyl-2-oxo-1,2-dihydropyrimidin-1-yl)butanoic acid hydrochloride; 4,6-Dimethyl-1-(4-carboxybutyl)pyrimidin-2(1H)-one hydrochloride; Butyric acid, 4-(4,6-dimethyl-2-oxo-2H-pyrimidin-1-yl)-, hydrochloride; 4-(4,6-Dimethyl-2-oxopyrimidin-1(2H)-yl)butanoic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(4,6-Dimethyl-2-Oxo-2H-Pyrimidin-1-Yl)-Butyric Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.