Description

2,2,2-Trifluoro-1-(4-Fluorophenyl)Ethylamine Hydrochloride is a high-purity fluorinated amine hydrochloride salt, a key building block in advanced organic synthesis. This compound is valued for its unique trifluoromethyl and fluorophenyl groups, which are critical for modulating the physicochemical properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a chiral amine component for constructing sophisticated ligands used in asymmetric catalysis.
• Material Science: Incorporated into specialty polymers and advanced materials to impart unique surface properties and chemical resistance.
• Fluorine Chemistry Library: A valuable compound for building diverse screening libraries in medicinal and discovery chemistry programs.

Basic Information

Product Name	2,2,2-Trifluoro-1-(4-Fluorophenyl)Ethylamine Hydrochloride
CAS No.	1184980-60-6
Molecular Formula	C8H8ClF4N
Molecular Weight	229.60 g/mol
Synonyms	1-(4-Fluorophenyl)-2,2,2-trifluoroethanamine Hydrochloride; α-(Trifluoromethyl)-4-fluorobenzeneethanamine Hydrochloride; 4-Fluoro-α-(trifluoromethyl)benzylamine Hydrochloride; (R/S)-1-(4-Fluorophenyl)-2,2,2-trifluoroethylamine HCl; 2,2,2-Trifluoro-1-(4-fluorophenyl)ethan-1-amine Hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2,2,2-Trifluoro-1-(4-Fluorophenyl)Ethylamine Hydrochloride is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure the material meets the rigorous standards required for research and scale-up. A detailed Certificate of Analysis (COA), including purity assay and impurity profile by HPLC, is supplied with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.