Description

2-Bromo-4-Fluoroaniline Hydrochloride is an important halogenated aniline derivative, primarily utilized as a versatile synthetic intermediate in advanced organic chemistry. Its value lies in providing a reactive aromatic amine scaffold with orthogonal halogen handles, enabling precise molecular construction for complex target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key building block for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing fluorinated and brominated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the halogen substituents modulate bioactivity and stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as a key intermediate for synthesizing complex halogenated azo dyes and high-performance pigments.
• Cross-Coupling Reactions: The bromo and fluoro substituents make it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create biaryl and other complex structures.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, affinity labels, and linker molecules for studying biological systems.

Basic Information

Product Name	2-Bromo-4-Fluoroaniline Hydrochloride
CAS No.	1184937-19-6
Molecular Formula	C6H6BrClFN
Molecular Weight	226.47 g/mol
Synonyms	2-Bromo-4-fluoroaniline HCl; 4-Fluoro-2-bromoaniline hydrochloride; Benzenamine, 2-bromo-4-fluoro-, hydrochloride (1:1); 2-Bromo-4-fluoro-phenylamine hydrochloride; 2-Bromo-4-fluoroaniline monohydrochloride; 4-Fluoro-2-bromo-benzenamine hydrochloride; 2-Bromo-4-fluoroaniline, HCl salt
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluoroaniline Hydrochloride is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, residual solvent analysis, and identity confirmation via FT-IR and NMR. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after initial opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.