Description

1-(2-Amino-3-Fluorophenyl)Piperidin-4-Ol is a high-purity fluorinated piperidine derivative, serving as a critical pharmaceutical intermediate and research chemical for advanced organic synthesis. Its unique structure, featuring both an aromatic amine and a piperidinol group, makes it a valuable building block for developing novel bioactive molecules, particularly in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors seeking to create new drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially for central nervous system (CNS) targets and kinase inhibitors.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Building block for creating novel pesticides and herbicides that leverage the fluorine atom for enhanced activity and stability.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and enzyme functions.
• Organic Synthesis: Serves as a versatile intermediate for constructing complex heterocyclic compounds and fluorinated aromatic systems.
• Material Science Research: Potential monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	1-(2-Amino-3-Fluorophenyl)Piperidin-4-Ol
CAS No.	1184648-78-9
Molecular Formula	C11H15FN2O
Molecular Weight	210.25 g/mol
Synonyms	4-Piperidinol, 1-(2-amino-3-fluorophenyl)-; 1-(2-Amino-3-fluorophenyl)-4-piperidinol; 2-Amino-3-fluoro-1-(4-hydroxy-1-piperidinyl)benzene; 1-(2-Amino-3-fluorophenyl)piperidin-4-ol; 1-(2-Amino-3-fluorophenyl)-4-hydroxypiperidine; 4-Hydroxy-1-(2-amino-3-fluorophenyl)piperidine
EINECS	Contact for details

Quality Control

Our production of 1-(2-Amino-3-Fluorophenyl)Piperidin-4-Ol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade specifications. Our quality systems are designed to guarantee batch-to-batch consistency and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.