Description

1-(3-Fluoro-4-Methylphenyl)Propan-1-Amine is a high-purity fluorinated aromatic amine building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorinated motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, due to the fluorine atom's ability to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine substituent can enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to develop fluorescent tags and molecular probes for studying biological processes and diagnostics.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-(3-Fluoro-4-Methylphenyl)Propan-1-Amine
CAS No.	1184551-53-8
Molecular Formula	C10H14FN
Molecular Weight	167.22 g/mol
Synonyms	1-(3-Fluoro-4-methylphenyl)propan-1-amine; 3-Fluoro-4-methylpropiophenone imine (reduction precursor); 1-Amino-1-(3-fluoro-4-methylphenyl)propane; 3-Fluoro-4-methyl-β-methylphenethylamine; 1-(3-Fluoro-p-tolyl)propan-1-amine; 3'-Fluoro-4'-methylpropiophenone imine; Benzenepropanamine, 3-fluoro-4-methyl-
EINECS	Contact for details

Quality Control

Our 1-(3-Fluoro-4-Methylphenyl)Propan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' needs in regulated development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Typical 98-99%)
Water Content (KF)	≤ 0.5% w/w
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.