Description

4-[3,4-Dihydro-1(2H)-Quinolinyl]-3-(Trifluoromethyl)Aniline is a specialized aromatic amine derivative featuring a tetrahydroquinoline and a trifluoromethylphenyl moiety. This compound serves as a high-value intermediate in advanced organic synthesis, prized for its unique structural motifs that can impart desirable properties to target molecules. It is primarily needed by pharmaceutical R&D and agrochemical laboratories for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functional dyes, ligands, or monomers aimed at creating specialty polymers with specific optical or electronic properties.
• Chemical Biology: Employed as a probe or scaffold in the design of enzyme inhibitors or receptor modulators for biological studies.
• Advanced Organic Synthesis: A versatile reagent for constructing complex nitrogen-containing heterocycles and fluorinated aromatic systems.

Basic Information

Product Name	4-[3,4-Dihydro-1(2H)-Quinolinyl]-3-(Trifluoromethyl)Aniline
CAS No.	1184441-83-5
Molecular Formula	C16H15F3N2
Molecular Weight	292.30 g/mol
Synonyms	3-(Trifluoromethyl)-4-(1,2,3,4-tetrahydroquinolin-1-yl)aniline; 4-(1,2,3,4-Tetrahydroquinolin-1-yl)-3-(trifluoromethyl)benzenamine; 1-[4-Amino-2-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydroquinoline; 4-(3,4-Dihydro-1(2H)-quinolinyl)-3-(trifluoromethyl)benzenamine; 3-Trifluoromethyl-4-(1,2,3,4-tetrahydroquinolin-1-yl)phenylamine; CAS 1184441-83-5; 1184441-83-5
EINECS	Contact for details

Quality Control

Our production of 4-[3,4-Dihydro-1(2H)-Quinolinyl]-3-(Trifluoromethyl)Aniline adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. All materials undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry for identity confirmation and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and related substances is provided with each shipment. We support development and scale-up projects with custom synthesis and specification tailoring upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.