Description

2-Fluoro-6-(Pyrrolidin-1-Yl)Aniline is a high-purity, advanced pharmaceutical intermediate featuring a unique aniline core substituted with fluorine and a pyrrolidine group. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new compounds with enhanced biological activity and selectivity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially in oncology and central nervous system (CNS) therapeutic research.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its fluorine-containing structure for improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to create fluorescent or affinity tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital component for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke chemical synthesis services.

Basic Information

Product Name	2-Fluoro-6-(Pyrrolidin-1-Yl)Aniline
CAS No.	1183840-96-1
Molecular Formula	C10H13FN2
Molecular Weight	180.22 g/mol
Synonyms	2-Fluoro-6-(1-pyrrolidinyl)aniline; 2-Fluoro-6-pyrrolidin-1-ylaniline; 1-(3-Amino-2-fluorophenyl)pyrrolidine; 2-Fluoro-6-pyrrolidinoaniline; Benzenamine, 2-fluoro-6-(1-pyrrolidinyl)-; 1183840-96-1; 2-Fluoro-6-pyrrolidinylaniline
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-(Pyrrolidin-1-Yl)Aniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.