Description

n-Ethyl-4-Nitro-2-(Trifluoromethyl)Aniline is a specialized aromatic amine derivative featuring nitro and trifluoromethyl substituents, which confer unique electronic and steric properties. This compound is a critical high-purity intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds with enhanced bioactivity and stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas requiring fluorinated motifs for improved metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental persistence.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials or emissive layer dopants in display and lighting technologies.
• Liquid Crystal & Dye Intermediates: Employed in the production of specialty dyes and liquid crystal compounds for electronic displays.
• Material Science Research: Acts as a monomer or functionalization agent in the development of advanced polymers and coatings with specific chemical resistance.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating complex nitrogen-containing architectures.

Basic Information

Product Name	n-Ethyl-4-Nitro-2-(Trifluoromethyl)Aniline
CAS No.	1183678-32-1
Molecular Formula	C9H9F3N2O2
Molecular Weight	234.18 g/mol
Synonyms	4-Nitro-2-(trifluoromethyl)-N-ethylaniline; 2-(Trifluoromethyl)-4-nitro-N-ethylaniline; N-Ethyl-4-nitro-2-(trifluoromethyl)benzenamine; 1-Ethylamino-4-nitro-2-(trifluoromethyl)benzene; Benzenamine, N-ethyl-4-nitro-2-(trifluoromethyl)-; N-Ethyl-4-nitro-α,α,α-trifluoro-o-toluidine
EINECS	Contact for details

Quality Control

Our n-Ethyl-4-Nitro-2-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable batch-to-batch consistency for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider packaging under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.