Description

2-Fluoro-6-[(Tetrahydrofuran-2-Yl)Methoxy]Aniline is a specialized fluorinated aniline derivative featuring a tetrahydrofuranylmethoxy substituent, making it a valuable chiral building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for use in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atom and chiral center can enhance biological activity and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials requiring specific fluorinated aromatic components.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and heterocycle formation.

Basic Information

Product Name	2-Fluoro-6-[(Tetrahydrofuran-2-Yl)Methoxy]Aniline
CAS No.	1183643-73-3
Molecular Formula	C11H14FNO2
Molecular Weight	211.23 g/mol
Synonyms	2-Fluoro-6-[(tetrahydro-2-furanyl)methoxy]benzenamine; 2-Fluoro-6-(tetrahydrofuran-2-ylmethoxy)aniline; 2-Fluoro-6-[(oxolan-2-yl)methoxy]aniline; 2-Fluoro-6-[(tetrahydrofuran-2-yl)methoxy]phenylamine; 2-Fluoro-6-(THF-2-ylmethoxy)aniline; Benzenamine, 2-fluoro-6-[(tetrahydro-2-furanyl)methoxy]-; 1183643-73-3
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-[(Tetrahydrofuran-2-Yl)Methoxy]Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.