Description

2-(2,4-Difluorophenyl)Benzaldehyde is a high-purity fluorinated aromatic aldehyde building block. This compound is critical for synthesizing advanced pharmaceutical intermediates and functional materials due to its reactive aldehyde group and substituted difluorophenyl ring. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and ligands.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and pesticides with enhanced activity and selectivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Monomer or precursor for synthesizing fluorinated polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Serves as a starting point for creating fluorescent tags, molecular probes, and bioconjugation reagents.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for scale-up and production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	2-(2,4-Difluorophenyl)Benzaldehyde
CAS No.	1183323-64-9
Molecular Formula	C13H8F2O
Molecular Weight	218.20 g/mol
Synonyms	2-(2,4-Difluorophenyl)benzaldehyde; [1,1'-Biphenyl]-2-carboxaldehyde, 2',4'-difluoro-; 2',4'-Difluoro[1,1'-biphenyl]-2-carboxaldehyde; 2-Formyl-2',4'-difluorobiphenyl; (2,4-Difluorophenyl)benzaldehyde; 2-(2,4-Difluorophenyl)benzenecarbaldehyde
EINECS	Contact for details

Quality Control

Our 2-(2,4-Difluorophenyl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for every shipment. We support development from milligram to kilogram scale with a commitment to reliable supply and traceable documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.