Description

2-Ethyl-1,3-Benzoxazole-5-Sulfonyl Chloride is a high-value, reactive sulfonyl chloride derivative used as a key synthetic intermediate in advanced organic synthesis. Its primary value lies in its role as a versatile building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce the 2-ethylbenzoxazole sulfonamide moiety into target structures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting enzymes where the sulfonamide group acts as a pharmacophore.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides that incorporate benzoxazole scaffolds for enhanced bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of advanced polymers and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a labeling reagent or affinity probe due to its reactive sulfonyl chloride group, which can modify specific amino acid residues.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing client-specific compounds.

Basic Information

Product Name	2-Ethyl-1,3-Benzoxazole-5-Sulfonyl Chloride
CAS No.	1183262-68-1
Molecular Formula	C9H8ClNO3S
Molecular Weight	245.68 g/mol
Synonyms	5-(Chlorosulfonyl)-2-ethyl-1,3-benzoxazole; 2-Ethyl-5-sulfonylchloride benzoxazole; 2-Ethylbenzoxazole-5-sulfonyl chloride; 1,3-Benzoxazole-5-sulfonyl chloride, 2-ethyl-; 1183262-68-1; 2-Ethyl-1,3-benzoxazol-5-ylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Ethyl-1,3-Benzoxazole-5-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.