Description

n-(Piperidin-4-Yl)Quinazolin-4-Amine CAS NO 1183120-04-8 is a high-purity, advanced pharmaceutical intermediate belonging to the quinazoline class of heterocyclic compounds. This compound is of significant commercial interest for its role as a critical building block in the synthesis of targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Chemical Biology Research: Used as a scaffold or probe in structure-activity relationship (SAR) studies and target identification.
• Medicinal Chemistry: Serves as a core structural motif for designing and optimizing new chemical entities with potential therapeutic activity.
• Bioconjugation: The amine and heterocyclic structure can be utilized for conjugation with biomolecules or other chemical moieties.
• High-Throughput Screening (HTS): Employed as a standard or test compound in drug discovery screening libraries.
• Custom Synthesis: Used as a starting material for the contract manufacturing of specialized APIs and fine chemicals.

Basic Information

Product Name	n-(Piperidin-4-Yl)Quinazolin-4-Amine
CAS No.	1183120-04-8
Molecular Formula	C13H16N4
Molecular Weight	228.30 g/mol
Synonyms	4-(Quinazolin-4-ylamino)piperidine; 4-Quinazolinamine, N-4-piperidinyl-; 4-(4-Piperidinylamino)quinazoline; N-(Piperidin-4-yl)quinazolin-4-amine; Quinazolin-4-amine, N-(4-piperidinyl)-; 1183120-04-8; N-(piperidin-4-yl)quinazolin-4-amine
EINECS	Contact for details

Quality Control

Our n-(Piperidin-4-Yl)Quinazolin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.