Description

4-(2,5-Difluorophenyl)Phenol is a high-purity fluorinated phenolic compound, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique difluorophenyl-substituted phenol structure, which imparts desirable electronic and steric properties for constructing complex molecules. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Science: Acts as a monomer or modifier in the synthesis of specialty polymers, including high-performance engineering plastics and resins.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in medicinal chemistry and material science for structure-activity relationship (SAR) studies.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized fluorinated dyes and pigments for high-value applications.

Basic Information

Product Name	4-(2,5-Difluorophenyl)Phenol
CAS No.	1181291-45-1
Molecular Formula	C12H8F2O
Molecular Weight	206.19 g/mol
Synonyms	4-(2,5-Difluorophenyl)phenol; 2',5'-Difluoro[1,1'-biphenyl]-4-ol; (2,5-Difluorophenyl)phenol; 4-Hydroxy-2',5'-difluorobiphenyl; 4-(2,5-Difluorophenyl)hydroxybenzene; Biphenyl-4-ol, 2',5'-difluoro-; Phenol, 4-(2,5-difluorophenyl)-
EINECS	Contact for details

Quality Control

Our 4-(2,5-Difluorophenyl)Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.