Description

2-Chloro-5-(Trifluoromethyl)Aniline Hydrochloride is a high-purity, halogenated aniline derivative salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive aromatic amine handle with enhanced lipophilicity and metabolic stability, crucial for developing high-performance compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides, where the trifluoromethyl and chloro groups contribute to biological activity and environmental persistence.
• Material Science: Used in the production of specialty polymers, liquid crystals, and dyes, where its aromatic structure and halogen atoms modify material properties.
• Organic Synthesis: Versatile reagent for introducing the 2-chloro-5-(trifluoromethyl)aniline moiety into more complex molecular architectures via coupling, condensation, or functional group transformation reactions.
• Research & Development: Critical compound for medicinal chemistry programs and process chemistry optimization in both academic and industrial R&D laboratories.

Basic Information

Product Name	2-Chloro-5-(Trifluoromethyl)Aniline Hydrochloride
CAS No.	1179444-82-6
Molecular Formula	C7H6ClF3N · HCl
Molecular Weight	246.49 g/mol
Synonyms	2-Chloro-5-(trifluoromethyl)benzenamine hydrochloride; 2-Chloro-alpha,alpha,α-trifluoro-p-toluidine hydrochloride; 2-Chloro-5-(trifluoromethyl)phenylamine hydrochloride; 2-Chloro-5-trifluoromethylaniline HCl; 2-Chloro-5-trifluoromethylaniline hydrochloride; 2-Chloro-α,α,α-trifluoro-p-toluidine hydrochloride; Benzenamine, 2-chloro-5-(trifluoromethyl)-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(Trifluoromethyl)Aniline Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to meet exacting customer specifications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.