Description

2-Fluoro-6-(4-Methylpiperazin-1-Yl)Aniline is a high-purity, advanced pharmaceutical intermediate featuring a unique fluorinated aniline structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the fluorine atom and piperazine moiety can enhance biological activity and environmental stability.
• Organic Synthesis Reagent: Serves as a versatile precursor for palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) to create complex aromatic amines.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying enzyme function and protein-ligand interactions.
• Material Science Research: Investigated as a monomer or functionalizing agent for creating specialty polymers with specific electronic or surface properties.

Basic Information

Product Name	2-Fluoro-6-(4-Methylpiperazin-1-Yl)Aniline
CAS No.	1179276-91-5
Molecular Formula	C11H16FN3
Molecular Weight	209.27 g/mol
Synonyms	1-(3-Amino-2-fluorophenyl)-4-methylpiperazine; 2-Fluoro-6-(4-methyl-1-piperazinyl)aniline; 2-Fluoro-6-(4-methylpiperazin-1-yl)benzenamine; 2-Fluoro-6-(N-methylpiperazino)aniline; 1179276-91-5; 2-Fluoro-6-(4-methylpiperazin-1-yl)phenylamine
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-(4-Methylpiperazin-1-Yl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. The compound is light-sensitive and easily oxidized; therefore, containers should be kept sealed and allowed to reach room temperature before opening to minimize moisture ingress and oxidative degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.