Description

3,5-Difluoro-4-(Pyrrolidin-1-Yl)Aniline is a high-value, fluorinated aniline derivative featuring a pyrrolidine substituent, serving as a critical building block in advanced organic synthesis. Its molecular architecture makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atoms and amine group can enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or functionalization agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Acts as a versatile building block for palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) and for introducing the difluoroaniline pharmacophore into more complex structures.
• Dye and Pigment Industry: Employed in the synthesis of specialized fluorinated dyes and pigments that offer improved lightfastness and color properties.

Basic Information

Item	Details
Product Name	3,5-Difluoro-4-(Pyrrolidin-1-Yl)Aniline
CAS No.	1179140-55-6
Molecular Formula	C10H12F2N2
Molecular Weight	198.21 g/mol
Synonyms	4-(Pyrrolidin-1-yl)-3,5-difluoroaniline; 3,5-Difluoro-4-(1-pyrrolidinyl)aniline; 3,5-Difluoro-4-pyrrolidin-1-ylaniline; 1-(2,6-Difluoro-4-aminophenyl)pyrrolidine; 4-Amino-2,6-difluorophenylpyrrolidine; 1179140-55-6; Aniline, 3,5-difluoro-4-(1-pyrrolidinyl)-
EINECS	Contact for details

Quality Control

Every batch of 3,5-Difluoro-4-(Pyrrolidin-1-Yl)Aniline is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency that meets the stringent requirements of research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.