Description

2-[2-Amino(Ethyl)-4-(Trifluoromethyl)Anilino]-1-Ethanol is a specialized organic intermediate featuring a unique trifluoromethyl-substituted aniline and ethanolamine structure. This compound is valued for its role as a key building block in the synthesis of advanced pharmaceutical and agrochemical active ingredients. It is primarily sought by research and development teams and production chemists in the fine chemical and life science industries for creating novel molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve lipophilicity and biological efficacy.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands or organocatalysts used in asymmetric synthesis and metal-catalyzed cross-coupling reactions.
• Material Science Research: Investigated as a monomer or functional additive for specialty polymers, coatings, and advanced materials requiring specific surface properties or fluorine content.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions in biochemical research.

Basic Information

Product Name	2-[2-Amino(Ethyl)-4-(Trifluoromethyl)Anilino]-1-Ethanol
CAS No.	1178787-47-7
Molecular Formula	C11H15F3N2O
Molecular Weight	248.25 g/mol
Synonyms	1-Ethanol, 2-[2-aminoethyl-[4-(trifluoromethyl)phenyl]amino]-; 2-({2-Aminoethyl}[4-(trifluoromethyl)phenyl]amino)ethan-1-ol; N-(2-Aminoethyl)-4-(trifluoromethyl)anilinoethanol; 2-[(2-Aminoethyl)(4-trifluoromethylphenyl)amino]ethanol; 2-[2-Aminoethyl(4-trifluoromethylphenyl)amino]ethanol; 2-[[(4-Trifluoromethyl)phenyl](2-aminoethyl)amino]ethanol
EINECS	Contact for details

Quality Control

Our production of 2-[2-Amino(Ethyl)-4-(Trifluoromethyl)Anilino]-1-Ethanol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are subjected to rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.