Description

4-(4-Chloro-7-(Methylsulfonyl)-6,7-Dihydro-5H-Pyrrolo[2,3-D]Pyrimidin-2-Yl)Morpholine is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrrolopyrimidine class of heterocyclic compounds. This compound serves as a critical building block in the synthesis of complex small-molecule drugs, particularly kinase inhibitors targeting various therapeutic areas. It is essential for research and development organizations and production facilities in the pharmaceutical and biotechnology sectors requiring reliable, high-quality raw materials for API synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for targeted cancer therapies.
• Kinase Inhibitor Development: Core scaffold for the research and production of novel kinase inhibitors used in oncology and inflammatory disease treatment.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Process Chemistry & Scale-Up: Employed in route scouting, process development, and cGMP manufacturing for clinical trial material and commercial drug supply.
• Contract Manufacturing (CDMO): Supplied to contract development and manufacturing organizations for client-specific synthesis projects.
• Biochemical Research: Used as a tool compound in biochemical assays to study enzyme function and cellular signaling pathways.

Basic Information

Product Name	4-(4-Chloro-7-(Methylsulfonyl)-6,7-Dihydro-5H-Pyrrolo[2,3-D]Pyrimidin-2-Yl)Morpholine
CAS No.	1178564-27-6
Molecular Formula	C11H15ClN4O3S
Molecular Weight	318.78 g/mol
Synonyms	4-(4-Chloro-7-(methylsulfonyl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-2-yl)morpholine; 2-Morpholino-4-chloro-7-(methylsulfonyl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-2-morpholino-7-(methylsulfonyl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine; Pyrrolo[2,3-d]pyrimidine, 4-(4-chloro-7-(methylsulfonyl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-2-yl)morpholine; CAS 1178564-27-6
EINECS	Contact for details

Quality Control

Our 4-(4-Chloro-7-(Methylsulfonyl)-6,7-Dihydro-5H-Pyrrolo[2,3-D]Pyrimidin-2-Yl)Morpholine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with agreed specifications. We support development and commercial projects requiring material traceability and data integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.