Description

n-(2,2-Difluoroethyl)-n-(4-Methylphenyl)Amine is a specialized fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the difluoroethyl group, enabling the introduction of fluorine motifs critical for modulating the physical and biological properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, as well as by material scientists exploring advanced functional polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly where fluorine substitution is used to enhance metabolic stability, bioavailability, or membrane permeability.
• Agrochemical Synthesis: Used in constructing novel herbicides, fungicides, and insecticides, where the fluorine atoms can improve efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in advanced display technologies.
• Functional Polymer Monomer: Incorporated into specialty polymers to impart unique surface properties, chemical resistance, or optical characteristics.
• Organic Electronics: Potential use in the synthesis of materials for organic light-emitting diodes (OLEDs) or semiconductors.
• Chemical Research & Development: A versatile reagent for academic and industrial research exploring new fluorination methodologies and novel chemical entities.

Basic Information

Item	Detail
Product Name	n-(2,2-Difluoroethyl)-n-(4-Methylphenyl)Amine
CAS No.	1178471-37-8
Molecular Formula	C9H11F2N
Molecular Weight	171.19 g/mol
Synonyms	N-(2,2-Difluoroethyl)-4-methylaniline; 4-Methyl-N-(2,2-difluoroethyl)aniline; N-(2,2-Difluoroethyl)-p-toluidine; p-Tolyl(2,2-difluoroethyl)amine; 1-(2,2-Difluoroethyl)-1-(4-methylphenyl)amine; N-(4-Methylphenyl)-2,2-difluoroethanamine; 2,2-Difluoro-N-(p-tolyl)ethanamine
EINECS	Contact for details

Quality Control

Our n-(2,2-Difluoroethyl)-n-(4-Methylphenyl)Amine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality system is designed to meet the stringent requirements of cGMP for advanced intermediates and supports compliance with global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.