Description

2-(4-Piperidinylthio)Pyrimidine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its unique heterocyclic structure, which serves as a critical scaffold in modern medicinal chemistry and drug discovery. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used as a versatile building block for constructing complex molecular libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as a synthetic intermediate for novel pesticides and herbicides, leveraging its pyrimidine core.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.

Basic Information

Product Name	2-(4-Piperidinylthio)Pyrimidine Hydrochloride
CAS No.	1177326-46-3
Molecular Formula	C9H14ClN3S
Molecular Weight	231.74 g/mol
Synonyms	2-((Piperidin-4-yl)thio)pyrimidine hydrochloride; 4-((Pyrimidin-2-yl)thio)piperidine hydrochloride; 2-Piperidin-4-ylsulfanyl-pyrimidine hydrochloride; Pyrimidine, 2-[(4-piperidinyl)thio]-, hydrochloride; 2-(4-Piperidylthio)pyrimidine HCl
EINECS	Contact for details

Quality Control

Our 2-(4-Piperidinylthio)Pyrimidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen or argon atmosphere) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.