Description

4-[5-(Methoxymethyl)-1,2,4-Oxadiazol-3-Yl]-2-Piperazin-1-Ylpyrimidine Dihydrochloride is a high-purity, non-nucleoside building block and advanced intermediate designed for pharmaceutical research and development. This compound is critical for medicinal chemists exploring novel therapeutic agents, particularly in the areas of kinase inhibition and central nervous system (CNS) disorders. It is primarily utilized by R&D laboratories and contract manufacturing organizations (CMOs) in the pharmaceutical and biotechnology sectors for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel small-molecule drug candidates.
• Kinase Inhibitor Research: Serves as a core scaffold in the development of potential kinase inhibitors for oncology and inflammatory diseases.
• CNS Drug Discovery: Used in research programs targeting neurological and psychiatric disorders.
• Chemical Biology Probes: Employed as a tool compound to study specific biological pathways and protein functions.
• Process Chemistry & Scale-up: Suitable for use in route scouting and optimization for API manufacturing.
• Contract Research & Development: Supplied to CROs and CDMOs for client-sponsored drug discovery projects.

Basic Information

Product Name	4-[5-(Methoxymethyl)-1,2,4-Oxadiazol-3-Yl]-2-Piperazin-1-Ylpyrimidine Dihydrochloride
CAS No.	1177093-11-6
Molecular Formula	C₁₂H₁₈Cl₂N₆O₂
Molecular Weight	349.22 g/mol
Synonyms	2-Piperazin-1-yl-4-[5-(methoxymethyl)-1,2,4-oxadiazol-3-yl]pyrimidine dihydrochloride; 4-(5-(Methoxymethyl)-1,2,4-oxadiazol-3-yl)-2-(piperazin-1-yl)pyrimidine dihydrochloride; 1177093-11-6; UNII-2F8V8L82AN; 2F8V8L82AN; CHEMBL3186662; BDBM50150871; AKOS009158950
EINECS	Contact for details

Quality Control

Our 4-[5-(Methoxymethyl)-1,2,4-Oxadiazol-3-Yl]-2-Piperazin-1-Ylpyrimidine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.