Description

2-Piperazin-1-Yl-4-[5-(Trifluoromethyl)-1,2,4-Oxadiazol-3-Yl]Pyrimidine Dihydrochloride is a high-purity, non-nucleoside pharmaceutical intermediate of significant interest in modern drug discovery. This compound is valued for its role as a key building block in the synthesis of novel therapeutic agents, particularly those targeting central nervous system disorders and other complex diseases. It is primarily utilized by research institutions, contract research organizations (CROs), and pharmaceutical companies engaged in the development of new chemical entities (NCEs).

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly for neurological and psychiatric targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Employed in the development of tool compounds for investigating specific biological pathways and protein functions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and pharmacology.

Basic Information

Product Name	2-Piperazin-1-Yl-4-[5-(Trifluoromethyl)-1,2,4-Oxadiazol-3-Yl]Pyrimidine Dihydrochloride
CAS No.	1177093-00-3
Molecular Formula	C11H12F3N7O · 2HCl
Molecular Weight	403.18 g/mol (Free base: 315.26 g/mol)
Synonyms	2-(Piperazin-1-yl)-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]pyrimidine dihydrochloride; 2-Piperazin-1-yl-4-(5-trifluoromethyl-[1,2,4]oxadiazol-3-yl)-pyrimidine dihydrochloride; 1177093-00-3; 2-(1-Piperazinyl)-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]pyrimidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-Piperazin-1-Yl-4-[5-(Trifluoromethyl)-1,2,4-Oxadiazol-3-Yl]Pyrimidine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.