Description

2-Nitro-5-(Trifluoromethyl)Benzaldehyde is a versatile aromatic aldehyde building block characterized by its nitro and trifluoromethyl substituents. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the trifluoromethyl group is prized for its ability to modulate biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and anticancer therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and biological efficacy.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Functional Material Research: Employed in the synthesis of organic electronic materials, liquid crystals, and dyes due to its electron-withdrawing substituents.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	2-Nitro-5-(Trifluoromethyl)Benzaldehyde
CAS No.	1176723-57-1
Molecular Formula	C8H4F3NO3
Molecular Weight	219.12 g/mol
Synonyms	5-(Trifluoromethyl)-2-nitrobenzaldehyde; 2-Nitro-α,α,α-trifluoro-p-tolualdehyde; Benzaldehyde, 2-nitro-5-(trifluoromethyl)-; 2-Nitro-5-trifluoromethylbenzaldehyde; α,α,α-Triflu-oro-2-nitro-p-tolualdehyde; 5-Trifluoromethyl-2-nitrobenzaldehyde; p-(Trifluoromethyl)-o-nitrobenzaldehyde
EINECS	Contact for details

Quality Control

Our 2-Nitro-5-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.