Description

Alamandine CAS NO 1176306-10-7 is a bioactive peptide and a key component of the renin-angiotensin system (RAS), recognized for its role as a ligand for the Mas-related G-protein coupled receptor member D (MrgD). This compound is of significant interest for its potential cardioprotective, anti-fibrotic, and anti-inflammatory properties, distinguishing it from other angiotensin peptides. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors for drug discovery, preclinical studies, and the development of novel therapeutic agents targeting cardiovascular and renal diseases.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating the protective arm of the renin-angiotensin system.
• Drug Discovery & Development: Serves as a lead compound or pharmacological tool for screening and developing new MrgD receptor agonists for therapeutic applications.
• Preclinical Studies: Employed in animal models to explore its effects on heart failure, hypertension, fibrosis, and metabolic disorders.
• Biochemical Assays: Utilized in receptor binding studies, cell signaling pathway analysis, and functional cellular assays.
• Diagnostic Development: Potential use in the development of assays to measure alamandine levels in biological samples for research purposes.

Basic Information

Product Name	Alamandine
CAS No.	1176306-10-7
Molecular Formula	C45H68N14O11
Molecular Weight	957.1 g/mol
Synonyms	Alamandine acetate; Angiotensin A (1-7); Ala1-Angiotensin (1-7); Asp-Arg-Val-Tyr-Ile-His-Pro; DRVYIHP; Alamandine peptide; MRGPRD ligand
EINECS	Contact for details

Quality Control

Our Alamandine is produced under stringent conditions to ensure the highest standards of purity and consistency, suitable for critical research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality guidelines to support your regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (Content)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC/IC)	Conforms
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.