Description

Fmoc-L-2,4-Dinitrophe CAS NO 1175832-19-5 is a specialized, protected amino acid derivative designed for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring high-purity building blocks to construct complex peptide sequences with precision. It is primarily utilized in pharmaceutical R&D, biotechnology, and academic laboratories focused on developing novel therapeutic peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected amino acid building block for the sequential assembly of peptides.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs) for peptide-based drugs.
• Bioconjugation: Facilitates the site-specific modification of peptides and proteins for diagnostic or therapeutic applications.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive compounds.
• Academic & Industrial Research: Essential for studies in medicinal chemistry, chemical biology, and proteomics.
• Custom Peptide Production: Used by CROs and CDMOs for the contract manufacturing of specific peptide sequences for clients.

Basic Information

Product Name	Fmoc-L-2,4-Dinitrophe
CAS No.	1175832-19-5
Molecular Formula	C₂₅H₂₁N₃O₈
Molecular Weight	491.45 g/mol
Synonyms	Fmoc-2,4-dinitrophenyl-L-phenylalanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2,4-dinitro-L-phenylalanine; Fmoc-Dnp-Phe-OH; Fmoc-L-Phe(2,4-Dnp)-OH; Nα-Fmoc-Nim-2,4-dinitrophenyl-L-histidine (common mis-association); Fmoc-protected DNP-phenylalanine; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-(2,4-dinitrophenyl)propanoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-L-2,4-Dinitrophe is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.