Description

cis-1-(9-H-Fluoren-9-Ylmethoxycarbonylamino)-Indan-2-Carboxylic Acid is a high-purity, protected amino acid derivative widely used as a critical building block in advanced organic synthesis. This compound is essential for the production of complex peptides and peptidomimetics, offering precise stereochemical control for researchers and manufacturers. It is primarily utilized by the pharmaceutical and biotechnology industries for drug discovery, process development, and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected intermediate for the controlled assembly of peptide chains.
• Pharmaceutical Research: Building block for the development of novel therapeutic peptides and peptidomimetic drug candidates.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for complex target molecules.
• Combinatorial Chemistry: Serves as a valuable scaffold in the generation of diverse chemical libraries for high-throughput screening.
• Bioconjugation: Facilitates the site-specific modification of peptides and proteins for diagnostic or therapeutic applications.
• Academic Research: Employed in synthetic organic chemistry studies and the development of new synthetic methodologies.

Basic Information

Product Name	cis-1-(9-H-Fluoren-9-Ylmethoxycarbonylamino)-Indan-2-Carboxylic Acid
CAS No.	1175651-61-2
Molecular Formula	C25H21NO4
Molecular Weight	399.44 g/mol
Synonyms	cis-1-[(9H-Fluoren-9-ylmethoxy)carbonylamino]indane-2-carboxylic acid; Fmoc-cis-1-aminoindane-2-carboxylic acid; Fmoc-Aic(2,3-cis)-OH; (1S,2R)-1-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2,3-dihydro-1H-indene-2-carboxylic acid; (1R,2S)-1-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2,3-dihydro-1H-indene-2-carboxylic acid; Fmoc-1-Aminoindane-2-carboxylic Acid (cis); Protected cis-1,2-Aminoindanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our cis-1-(9-H-Fluoren-9-Ylmethoxycarbonylamino)-Indan-2-Carboxylic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and MS for identity verification. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% cis-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.