Description

4-Fluoro-n-Methylaniline Hydrochloride is a high-purity organic salt derivative of a fluorinated aniline, serving as a critical building block in advanced chemical synthesis. This compound is valued for its role in introducing both fluorine and a protected amine functionality into target molecules, enabling the development of compounds with enhanced biological activity and metabolic stability. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and specialty crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) drugs and anticancer agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom can improve lipophilicity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a starting material for synthesizing fluorinated aromatic amines used in electronic display technologies.
• Dye & Pigment Manufacturing: Employed in the creation of specialized, light-fast fluorinated dyes and colorants.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for constructing complex nitrogen-containing heterocycles.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	4-Fluoro-n-Methylaniline Hydrochloride
CAS No.	1175090-48-8
Molecular Formula	C7H9ClFN
Molecular Weight	161.60 g/mol
Synonyms	N-Methyl-4-fluoroaniline hydrochloride; 4-Fluoro-N-methylaniline HCl; 1-Fluoro-4-(methylamino)benzene hydrochloride; 4-Fluoro-N-methylbenzenamine hydrochloride; p-Fluoro-N-methylaniline hydrochloride; N-Methyl-p-fluoroaniline hydrochloride; 4-Fluoro-N-methylphenylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Fluoro-n-Methylaniline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.