Description

2-Bromo-4-Fluoroaniline is a halogenated aniline derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the bromo-fluoroaniline moiety contributes to biological activity.
• Material Science: Serves as a monomer or functionalization agent in the production of specialty polymers, dyes, and liquid crystals.
• Organic Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce complex functionalities.
• Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	2-Bromo-4-Fluoroaniline
CAS No.	1175008-62-4
Molecular Formula	C6H5BrFN
Molecular Weight	190.01 g/mol
Synonyms	2-Bromo-4-fluoroaniline; 4-Fluoro-2-bromoaniline; 1-Amino-2-bromo-4-fluorobenzene; Benzenamine, 2-bromo-4-fluoro-; 2-Bromo-4-fluoro-phenylamine; 2-Br-4-F-C6H3NH2; (2-Bromo-4-fluorophenyl)amine
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluoroaniline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity against established specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents and acids. The container should be kept tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.