Description

3-[7-(Difluoromethyl)-5-(1-Ethylpyrazol-4-Yl)-[1,2,4]Triazolo[1,5-A]Pyrimidin-2-Yl]Propanoic Acid is a high-value, structurally complex heterocyclic compound that serves as a critical building block in modern synthetic chemistry. Its unique triazolopyrimidine core functionalized with difluoromethyl and propanoic acid groups makes it an essential intermediate for the development of novel active ingredients. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel small-molecule drug candidates, particularly in oncology and anti-infective research.
• Agrochemical Research: Advanced intermediate in the development of next-generation fungicides, herbicides, and insecticides with improved efficacy and environmental profiles.
• Chemical Biology Probe: Used in medicinal chemistry to study enzyme inhibition and structure-activity relationships (SAR) due to its privileged heterocyclic scaffold.
• Material Science Research: Potential precursor for functionalized organic materials and ligands for metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	3-[7-(Difluoromethyl)-5-(1-Ethylpyrazol-4-Yl)-[1,2,4]Triazolo[1,5-A]Pyrimidin-2-Yl]Propanoic Acid
CAS No.	1174874-40-8
Molecular Formula	C15H14F2N6O2
Molecular Weight	348.31 g/mol
Synonyms	3-[7-(Difluoromethyl)-5-(1-ethyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid; 1174874-40-8; 3-(7-(Difluoromethyl)-5-(1-ethyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)propanoic acid; 1-Ethyl-4-[7-(difluoromethyl)-2-(2-carboxyethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]pyrazole; Propanoic acid, 3-[7-(difluoromethyl)-5-(1-ethyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-
EINECS	Contact for details

Quality Control

Our 3-[7-(Difluoromethyl)-5-(1-Ethylpyrazol-4-Yl)-[1,2,4]Triazolo[1,5-A]Pyrimidin-2-Yl]Propanoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the stringent requirements for advanced research and development. Certificates of Analysis (COA) detailing purity, impurities, and full analytical data are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.