Description

3-[7-(Difluoromethyl)-5-(1-Methylpyrazol-3-Yl)-[1,2,4]Triazolo[1,5-A]Pyrimidin-2-Yl]Propanoic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new chemical entities (NCEs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly in oncology and anti-infective therapeutic areas.
• Agrochemical Research: Used as a key scaffold in the development of new-generation herbicides and fungicides with specific modes of action.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme inhibition and protein-ligand interactions due to its triazolopyrimidine core.
• Material Science Research: Investigated for the development of specialty polymers and organic electronic materials with unique properties.
• Process Chemistry & Scale-Up: Supplied to CDMOs for process optimization, route scouting, and the production of kilogram-to-ton quantities for clinical trials.

Basic Information

Item	Detail
Product Name	3-[7-(Difluoromethyl)-5-(1-Methylpyrazol-3-Yl)-[1,2,4]Triazolo[1,5-A]Pyrimidin-2-Yl]Propanoic Acid
CAS No.	1174867-81-2
Molecular Formula	C14H12F2N6O2
Molecular Weight	334.28 g/mol
Synonyms	3-[7-(Difluoromethyl)-5-(1-methyl-1H-pyrazol-3-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]propanoic acid; 1174867-81-2; 3-(7-(Difluoromethyl)-5-(1-methyl-1H-pyrazol-3-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)propanoic acid; 2-[3-Carboxypropyl]-7-(difluoromethyl)-5-(1-methylpyrazol-3-yl)-[1,2,4]triazolo[1,5-a]pyrimidine; DFMP-Triazolopyrimidine Propanoic Acid
EINECS	Contact for details

Quality Control

Our production of 3-[7-(Difluoromethyl)-5-(1-Methylpyrazol-3-Yl)-[1,2,4]Triazolo[1,5-A]Pyrimidin-2-Yl]Propanoic Acid adheres to strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure compliance with research and development grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.