Description

4-(4-Bromo-1H-Pyrazol-1-Yl)Benzenesulfonyl Chloride is a high-purity, multi-functional chemical building block primarily used in advanced organic synthesis. This compound matters for its role as a key sulfonylation reagent and heterocyclic intermediate, enabling the construction of complex molecules with precision. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting kinase inhibition and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its bromo-pyrazole and sulfonyl chloride functionalities.
• Material Science Research: Serves as a precursor for creating functional polymers, liquid crystals, or organic electronic materials due to its aromatic and heterocyclic structure.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and the development of chemical probes or activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical companies for use in custom synthesis projects and scale-up processes.

Basic Information

Product Name	4-(4-Bromo-1H-Pyrazol-1-Yl)Benzenesulfonyl Chloride
CAS No.	1174064-62-0
Molecular Formula	C9H6BrClN2O2S
Molecular Weight	321.58 g/mol
Synonyms	4-(4-Bromo-1H-pyrazol-1-yl)benzenesulfonyl chloride; 1-[4-(Chlorosulfonyl)phenyl]-4-bromo-1H-pyrazole; 4-Bromo-1-[4-(chlorosulfonyl)phenyl]-1H-pyrazole; Benzenesulfonyl chloride, 4-(4-bromo-1H-pyrazol-1-yl)-; 1174064-62-0
EINECS	Contact for details

Quality Control

Our 4-(4-Bromo-1H-Pyrazol-1-Yl)Benzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a sulfonyl chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.