Description

6-Chloro-5-Cyclopropylpyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate with a distinct pyrimidine core structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that leverage the pyrimidine moiety for biological activity.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating chemical probes and tool compounds to study biological pathways.
• Material Science: Investigated as a monomer or precursor for specialty polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	6-Chloro-5-Cyclopropylpyrimidin-4-Amine
CAS No.	1174007-83-0
Molecular Formula	C7H8ClN3
Molecular Weight	169.61 g/mol
Synonyms	4-Amino-6-chloro-5-cyclopropylpyrimidine; 5-Cyclopropyl-6-chloropyrimidin-4-amine; 6-Chloro-5-cyclopropyl-4-pyrimidinamine; 6-Chloro-5-cyclopropylpyrimidin-4-ylamine; 4-Pyrimidinamine, 6-chloro-5-cyclopropyl-
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-Cyclopropylpyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports both research-grade and cGMP-compliant supply chains for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.