Description

5-(5-((4-Cyclopentylpiperazin-1-yl)sulfonyl)-2-ethoxyphenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one is a high-purity, non-nucleoside heterocyclic compound designed for advanced pharmaceutical research and development. This molecule serves as a critical pharmacological reference standard and a key synthetic intermediate in the discovery of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions focused on medicinal chemistry and drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting specific enzyme pathways.
• Biochemical Research: Used as a reference standard and tool compound in enzyme inhibition assays and mechanism-of-action studies.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) optimization in drug discovery programs.
• High-Throughput Screening (HTS): Employed as a test compound in screening libraries to identify new biological activities.
• Analytical Standard: Provides a certified reference material for method development and validation in quality control laboratories.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and pharmacology.

Basic Information

Product Name	5-(5-((4-Cyclopentylpiperazin-1-yl)sulfonyl)-2-ethoxyphenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
CAS No.	1173706-34-7
Molecular Formula	C26H36N6O4S
Molecular Weight	528.67 g/mol
Synonyms	1173706-34-7; 1H-Pyrazolo[4,3-d]pyrimidin-7(6H)-one, 5-[5-[(4-cyclopentyl-1-piperazinyl)sulfonyl]-2-ethoxyphenyl]-1-methyl-3-propyl-; Tadalafil Impurity; Tadalafil Related Compound; PDE5 Inhibitor Intermediate; Pyrazolopyrimidinone Derivative; Sulfonylpiperazine Compound
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to stringent ISO 9001 quality management systems. Every batch is subjected to comprehensive analytical characterization, including HPLC purity analysis, NMR, and mass spectrometry for structural confirmation. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.