Description

Methyl 2-(5-Bromo-2-Pyrimidinyl)-2-Cyanoacetate is a high-value pyrimidine derivative and versatile chemical building block essential for advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique bromo-cyanoacetate functionalization enables precise molecular construction. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for creating complex heterocyclic structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a monomer or functionalizing agent in the creation of advanced polymers and organic electronic materials.
• Chemical Synthesis: A versatile reagent for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and discovery chemistry projects.

Basic Information

Product Name	Methyl 2-(5-Bromo-2-Pyrimidinyl)-2-Cyanoacetate
CAS No.	1171919-13-3
Molecular Formula	C8H6BrN3O2
Molecular Weight	256.06 g/mol
Synonyms	Methyl (5-bromopyrimidin-2-yl)cyanoacetate; 2-Cyano-2-(5-bromo-2-pyrimidinyl)acetic acid methyl ester; Methyl 2-cyano-2-(5-bromo-2-pyrimidinyl)acetate; Acetic acid, 2-cyano-2-(5-bromo-2-pyrimidinyl)-, methyl ester; 1171919-13-3
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(5-Bromo-2-Pyrimidinyl)-2-Cyanoacetate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.