Description

5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidin-4(3H)-One Hydrochloride is a high-purity pharmaceutical intermediate and building block with the CAS number 1171334-07-8. This heterocyclic compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology: Serves as a probe or precursor in the study of biological pathways and target validation.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to construct advanced, high-value molecular architectures.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidin-4(3H)-One Hydrochloride
CAS No.	1171334-07-8
Molecular Formula	C7H10N3O·HCl
Molecular Weight	187.63 g/mol (Free base: 152.18 g/mol)
Synonyms	3,4,6,7-Tetrahydro-4-oxopyrido[3,4-d]pyrimidine hydrochloride; 4(3H)-Pyrimidinone, 5,6,7,8-tetrahydro-3,4-dipyrido-, hydrochloride; 5,6,7,8-Tetrahydro-3,4-dipyrido[3,4-d]pyrimidin-4(3H)-one hydrochloride; THPP Hydrochloride; Pyrido[3,4-d]pyrimidin-4(3H)-one, 5,6,7,8-tetrahydro-, hydrochloride
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidin-4(3H)-One Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.