Description

n-(3-Aminopropyl)Pyrimidin-2-Amine Dihydrochloride is a high-purity, dihydrochloride salt derivative of an aminopropylpyrimidine, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a primary amine and a pyrimidine ring, makes it an invaluable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical developers for applications in medicinal chemistry, including the synthesis of novel small molecule drug candidates and biologically active probes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Ligand Synthesis: Employed in the development of chelating agents, catalysts, and ligands for coordination chemistry and catalysis.
• Bioconjugation: The reactive amine group facilitates its use in linking biomolecules or attaching fluorescent tags for diagnostic applications.
• Agrochemical Development: Serves as an intermediate in the research and synthesis of novel crop protection agents and herbicides.
• Chemical Biology Probes: Utilized to create tool compounds for investigating biological processes and enzyme functions.

Basic Information

Item	Details
Product Name	n-(3-Aminopropyl)Pyrimidin-2-Amine Dihydrochloride
CAS No.	1171176-74-1
Molecular Formula	C7H13N5 · 2HCl
Molecular Weight	256.13 g/mol
Synonyms	2-Pyrimidinamine, N-(3-aminopropyl)-, dihydrochloride; N1-(Pyrimidin-2-yl)propane-1,3-diamine dihydrochloride; 3-((Pyrimidin-2-yl)amino)propan-1-amine dihydrochloride; N-(3-Aminopropyl)-2-pyrimidinamine dihydrochloride; 1,3-Propanediamine, N1-(2-pyrimidinyl)-, dihydrochloride; APPA dihydrochloride
EINECS	Contact for details

Quality Control

Every batch of n-(3-Aminopropyl)Pyrimidin-2-Amine Dihydrochloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. A detailed Certificate of Analysis (COA), including purity by HPLC, identity confirmation, and impurity profiles, is supplied with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.