Description

5-Bromo-7H-Pyrrolo[2,3-D]Pyrimidine-4-Carbonitrile is a high-value heterocyclic building block, a key intermediate in modern pharmaceutical and agrochemical research. Its molecular structure, featuring both bromo and cyano substituents on a fused pyrrolopyrimidine core, makes it a versatile precursor for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical industry for the synthesis of kinase inhibitors and other biologically active small molecules. Its reliable quality and consistent supply are critical for accelerating drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of targeted therapeutics, particularly protein kinase inhibitors used in oncology and inflammatory disease research.
• Agrochemical Research: Serves as a key precursor in developing novel active ingredients for crop protection products.
• Chemical Biology Probe Development: Used to create molecular probes for studying enzyme function and cellular signaling pathways.
• Organic Synthesis Scaffold: Provides a versatile heterocyclic core for medicinal chemistry programs, enabling further functionalization via cross-coupling and nucleophilic substitution reactions.
• Material Science Research: Investigated as a potential monomer or precursor for advanced organic electronic materials due to its electron-deficient aromatic system.

Basic Information

Product Name	5-Bromo-7H-Pyrrolo[2,3-D]Pyrimidine-4-Carbonitrile
CAS No.	1168106-92-0
Molecular Formula	C7H3BrN4
Molecular Weight	223.03 g/mol
Synonyms	5-Bromo-7H-pyrrolo[2,3-d]pyrimidine-4-carbonitrile; 4-Cyano-5-bromo-7H-pyrrolo[2,3-d]pyrimidine; 5-Bromo-4-cyanopyrrolo[2,3-d]pyrimidine; 5-Bromo-7H-pyrrolo[2,3-d]pyrimidine-4-carbonitrile; 5-Bromo-4-cyano-7H-pyrrolo[2,3-d]pyrimidine; 1168106-92-0; 5-Bromo-7H-pyrrolo[2,3-d]pyrimidine-4-carbonitrile (CAS 1168106-92-0)
EINECS	Contact for details

Quality Control

Our 5-Bromo-7H-Pyrrolo[2,3-D]Pyrimidine-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.