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2-(2,4-Difluorophenyl)-6-[3-(Dimethylamino)Acryloyl]-4-Methyl-1,2,4-Triazine-3,5(2H,4H)-Dione CAS NO 1164548-78-0


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CAS No.:1164548-78-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(2,4-Difluorophenyl)-6-[3-(Dimethylamino)Acryloyl]-4-Methyl-1,2,4-Triazine-3,5(2H,4H)-Dione is a sophisticated heterocyclic compound featuring a triazine-dione core functionalized with fluorinated phenyl and dimethylamino acryloyl groups. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for developing novel active ingredients.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in therapeutic areas targeting specific enzymes or receptors.
  • Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
  • Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex heterocyclic systems due to its reactive functional groups.
  • Agrochemical Development: Potential intermediate in the research and development of new crop protection agents and herbicides.
  • Material Science Research: Investigated for its potential application in creating specialty polymers or functional materials with unique properties.

Basic Information

Product Name 2-(2,4-Difluorophenyl)-6-[3-(Dimethylamino)Acryloyl]-4-Methyl-1,2,4-Triazine-3,5(2H,4H)-Dione
CAS No. 1164548-78-0
Molecular Formula C₁₆H₁₅F₂N₅O₃
Molecular Weight 363.32 g/mol
Synonyms 4-Methyl-2-(2,4-difluorophenyl)-6-[3-(dimethylamino)-1-oxo-2-propen-1-yl]-1,2,4-triazine-3,5(2H,4H)-dione; 6-[3-(Dimethylamino)acryloyl]-2-(2,4-difluorophenyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)-dione; 2-(2,4-Difluorophenyl)-6-[3-(dimethylamino)prop-2-enoyl]-4-methyl-1,2,4-triazine-3,5-dione; CAS 1164548-78-0; 1,2,4-Triazine-3,5(2H,4H)-dione, 2-(2,4-difluorophenyl)-6-[3-(dimethylamino)-1-oxo-2-propen-1-yl]-4-methyl-
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Quality Control

Our 2-(2,4-Difluorophenyl)-6-[3-(Dimethylamino)Acryloyl]-4-Methyl-1,2,4-Triazine-3,5(2H,4H)-Dione is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item Specification
Appearance Off-white to light yellow powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference standard
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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