Description

Methyl (E)-8-Methyl-4-Oxo-6-Styryl-3,4-Dihydro-2H,6H-Pyrimido[2,1-B][1,3]Thiazine-7-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research targeting specific therapeutic pathways. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug molecules, especially in medicinal chemistry research.
• API Development: Used in the research and development of new Active Pharmaceutical Ingredients (APIs) targeting various disease mechanisms.
• Organic Synthesis Building Block: Provides a complex, functionalized core structure for constructing novel heterocyclic compounds in academic and industrial research.
• Biochemical Research: Employed in studies to investigate biological activity and structure-activity relationships (SAR) of novel chemical entities.
• Process Chemistry: Utilized in scaling up synthetic routes from laboratory to pilot plant scale during drug development phases.

Basic Information

Product Name	Methyl (E)-8-Methyl-4-Oxo-6-Styryl-3,4-Dihydro-2H,6H-Pyrimido[2,1-B][1,3]Thiazine-7-Carboxylate
CAS No.	1164526-88-8
Molecular Formula	C19H18N2O3S
Molecular Weight	354.42 g/mol
Synonyms	Methyl (E)-8-methyl-4-oxo-6-styryl-3,4-dihydro-2H,6H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate; (E)-Methyl 8-methyl-4-oxo-6-styryl-3,4-dihydro-2H,6H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate; 2H,6H-Pyrimido[2,1-b][1,3]thiazine-7-carboxylic acid, 3,4-dihydro-8-methyl-4-oxo-6-(2-phenylethenyl)-, methyl ester, (E)-; Methyl 8-methyl-4-oxo-6-[(E)-2-phenylethenyl]-3,4-dihydro-2H,6H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl (E)-8-Methyl-4-Oxo-6-Styryl-3,4-Dihydro-2H,6H-Pyrimido[2,1-B][1,3]Thiazine-7-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Maximum Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.