Description

Methyl (4R)-4-(Dimethylamino)-L-Prolinate(Saltdata: 2Hcl) is a high-purity, chiral proline derivative, specifically the methyl ester hydrochloride salt of a dimethylamino-substituted L-proline. This compound is a critical chiral building block and intermediate in the synthesis of complex pharmaceutical molecules, offering precise stereochemical control. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs), particularly in areas like protease inhibitors and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs).
• Protease Inhibitor Synthesis: Used in the construction of complex molecules targeting proteases, such as HCV NS3/4A protease inhibitors.
• Asymmetric Synthesis: Serves as a chiral auxiliary or building block in stereoselective organic synthesis.
• Peptidomimetics Development: Integral for creating modified peptide structures with enhanced stability and biological activity.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies.
• Fine Chemical Production: Used in the custom synthesis of specialty chemicals for advanced applications.

Basic Information

Product Name	Methyl (4R)-4-(Dimethylamino)-L-Prolinate(Saltdata: 2Hcl)
CAS No.	1163706-98-6
Molecular Formula	C9H19Cl2N2O2
Molecular Weight	267.17 g/mol
Synonyms	Methyl (4R)-4-(dimethylamino)-L-prolinate dihydrochloride; (4R)-4-(Dimethylamino)-L-proline methyl ester hydrochloride; L-Proline, 4-(dimethylamino)-, methyl ester, hydrochloride (1:?); Methyl 4-(dimethylamino)-L-prolinate hydrochloride; (2S,4R)-1-Methyl 4-(dimethylamino)pyrrolidine-2-carboxylate hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl (4R)-4-(Dimethylamino)-L-Prolinate(Saltdata: 2Hcl) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.