Description

3-(3-Pyrrolyl)-D-Alanine is a non-proteinogenic amino acid derivative featuring a pyrrole moiety attached to the D-alanine backbone. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential as a specialized building block in peptide synthesis. It serves as a critical chiral intermediate for medicinal chemists and researchers developing novel bioactive molecules. Target industries include pharmaceutical R&D, biotechnology, and fine chemical synthesis for applications in drug discovery and development.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate unique structural motifs that can influence biological activity and stability.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new chemical space for therapeutic targets.
• Bioconjugation: Potential use in the development of antibody-drug conjugates (ADCs) or other bioconjugates due to its functional handles.
• Chemical Biology Probes: Serves as a component in the design of molecular probes for studying enzyme mechanisms or protein-protein interactions.
• Fine Chemical Synthesis: A specialized intermediate for the custom synthesis of complex, high-value organic molecules in contract research and manufacturing.

Basic Information

Product Name	3-(3-Pyrrolyl)-D-Alanine
CAS No.	1163688-37-6
Molecular Formula	C7H10N2O2
Molecular Weight	154.17 g/mol
Synonyms	D-3-(3-Pyrrolyl)alanine; (R)-2-Amino-3-(1H-pyrrol-3-yl)propanoic acid; 3-(1H-Pyrrol-3-yl)-D-alanine; D-Alanine, 3-(3-pyrrolyl)-; 1163688-37-6; (R)-3-(1H-Pyrrol-3-yl)alanine; 3-Pyrrolyl-D-alanine
EINECS	Contact for details

Quality Control

Our 3-(3-Pyrrolyl)-D-Alanine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.