Description

3-Chloro-2,4,6-Trifluorobenzaldehyde is a versatile fluorinated aromatic aldehyde building block of significant interest in advanced organic synthesis. Its value lies in the strategic combination of chlorine and fluorine substituents, which allows for selective functionalization and tuning of electronic properties in target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in displays and lighting.
• Cross-Coupling Reactions: The chlorine atom provides a handle for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to construct complex biaryl systems.
• Functional Dye & Pigment Intermediate: Employed in the synthesis of specialized fluorinated dyes and pigments with unique colorfastness and optical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical manufacturers and CROs/CMOs for custom synthesis projects and scale-up processes.

Basic Information

Product Name	3-Chloro-2,4,6-Trifluorobenzaldehyde
CAS No.	1160573-14-7
Molecular Formula	C7H2ClF3O
Molecular Weight	194.54 g/mol
Synonyms	2,4,6-Trifluoro-3-chlorobenzaldehyde; 3-Chloro-2,4,6-trifluorobenzenecarboxaldehyde; Benzaldehyde, 3-chloro-2,4,6-trifluoro-; 3-Chloro-2,4,6-trifluorobenzaldehyde (CAS 1160573-14-7)
EINECS	Contact for details

Quality Control

Our 3-Chloro-2,4,6-Trifluorobenzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.