Description

2,6-Difluoro-4-Iodo-Benzaldehyde is a versatile halogenated benzaldehyde derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This high-purity intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific fluorine and iodine functionalities into their target compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in fluorinated active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic materials, contributing to improved performance in display technologies and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira), enabling rapid diversification of molecular libraries.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs) due to its ability to modulate electronic properties.
• Fluorination Chemistry Studies: Acts as a model compound in methodological research for studying directed ortho-metalation and nucleophilic aromatic substitution reactions.

Basic Information

Product Name	2,6-Difluoro-4-Iodo-Benzaldehyde
CAS No.	1160573-10-3
Molecular Formula	C7H3F2IO
Molecular Weight	267.90 g/mol
Synonyms	4-Iodo-2,6-difluorobenzaldehyde; 2,6-Difluoro-4-iodobenzaldehyde; Benzaldehyde, 2,6-difluoro-4-iodo-; 4-Iodo-2,6-difluorobenzenecarboxaldehyde; 1160573-10-3; AI3-28635; SCHEMBL2180621; DTXSID90676669
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-4-Iodo-Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Heavy Metals	<10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.