Description

2,5-Difluoro-4-Nitrobenzenecarbaldehyde is a high-purity aromatic aldehyde building block characterized by its strategically positioned fluorine and nitro substituents. This compound matters for its role as a versatile and reactive intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluoro-nitrobenzene scaffold.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as dyes, pigments, and molecular semiconductors, due to its electron-withdrawing groups.
• Fluorescent Probe and Sensor Fabrication: The aldehyde group allows for conjugation, making it useful for synthesizing fluorescent tags and chemical sensors.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences and specialty chemicals markets.

Basic Information

Product Name	2,5-Difluoro-4-Nitrobenzenecarbaldehyde
CAS No.	1160474-72-5
Molecular Formula	C7H3F2NO3
Molecular Weight	187.10 g/mol
Synonyms	2,5-Difluoro-4-nitrobenzaldehyde; 4-Nitro-2,5-difluorobenzaldehyde; 2,5-Difluoro-4-nitrobenzenecarboxaldehyde; 2,5-Difluoro-4-nitro-benzaldehyde; Benzaldehyde, 2,5-difluoro-4-nitro-; (2,5-Difluoro-4-nitrophenyl)methanal
EINECS	Contact for details

Quality Control

Every batch of 2,5-Difluoro-4-Nitrobenzenecarbaldehyde is produced and tested under strict quality management systems to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability and documentation suitable for regulated industry applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under inert atmosphere where prolonged exposure is expected to maintain optimal purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.