Description

1-(6-Chloro-Pyrimidin-4-Yl)-Piperidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique piperidine-pyrimidine core structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Incorporated into the final synthetic route for active pharmaceutical ingredients, particularly in kinase inhibitor development.
• Agrochemical Research: Serves as a building block for developing novel crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological processes and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	1-(6-Chloro-Pyrimidin-4-Yl)-Piperidine-3-Carboxylic Acid
CAS No.	1160263-08-0
Molecular Formula	C10H10ClN3O2
Molecular Weight	239.66 g/mol
Synonyms	1-(6-Chloropyrimidin-4-yl)piperidine-3-carboxylic acid; 3-Piperidinecarboxylic acid, 1-(6-chloro-4-pyrimidinyl)-; 1-(6-Chloro-4-pyrimidinyl)-3-piperidinecarboxylic acid; 1-(6-Chloro-pyrimidin-4-yl)-piperidin-3-carbonsäure; 1160263-08-0; 1-(6-Chloro-4-pyrimidinyl)piperidine-3-carboxylic acid; 1-(6-Chloro-4-pyrimidinyl)-3-piperidinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(6-Chloro-Pyrimidin-4-Yl)-Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.