Description

(2-{[4-(4-Methylphenyl)-6-(Trifluoromethyl)Pyrimidin-2-Yl]Oxy}Ethyl)Amine is a high-purity, functionalized pyrimidine derivative designed for advanced chemical synthesis. This compound is valued for its unique trifluoromethyl and amino-ethoxy side chains, which are critical for modulating the physicochemical properties and biological activity of target molecules. It serves as a key pharmaceutical intermediate and agrochemical building block for research and development teams in life sciences and crop protection.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functional additive in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for designing enzyme inhibitors or receptor modulators.
• Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	(2-{[4-(4-Methylphenyl)-6-(Trifluoromethyl)Pyrimidin-2-Yl]Oxy}Ethyl)Amine
CAS No.	1160246-50-3
Molecular Formula	C14H14F3N3O
Molecular Weight	297.27 g/mol
Synonyms	2-({[4-(4-Methylphenyl)-6-(trifluoromethyl)pyrimidin-2-yl]oxy}ethyl)amine; 2-[2-[[4-(4-Methylphenyl)-6-(trifluoromethyl)pyrimidin-2-yl]oxy]ethyl]amine; 2-((4-p-Tolyl-6-(trifluoromethyl)pyrimidin-2-yl)oxy)ethan-1-amine; 4-(4-Methylphenyl)-6-(trifluoromethyl)-2-(2-aminoethoxy)pyrimidine; 2-Aminoethoxy-4-(4-methylphenyl)-6-(trifluoromethyl)pyrimidine; CAS 1160246-50-3
EINECS	Contact for details

Quality Control

Our (2-{[4-(4-Methylphenyl)-6-(Trifluoromethyl)Pyrimidin-2-Yl]Oxy}Ethyl)Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions or inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.