Description

7-(Difluoromethyl)Pyrazolo[1,5-A]Pyrimidine-6-Carboxylic Acid is a high-value, multifunctional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because its unique pyrazolopyrimidine core, functionalized with both a difluoromethyl group and a carboxylic acid, provides a versatile scaffold for constructing complex molecules with tailored properties. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the difluoromethyl group can enhance metabolic stability and bioavailability.
• Chemical Biology Probe Development: Serves as a core structure for creating tool compounds to study biological pathways and protein functions.
• Material Science Research: Potential precursor for the synthesis of specialized ligands or organic electronic materials due to its conjugated heterocyclic system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	7-(Difluoromethyl)Pyrazolo[1,5-A]Pyrimidine-6-Carboxylic Acid
CAS No.	1160246-20-7
Molecular Formula	C8H5F2N3O2
Molecular Weight	213.14 g/mol
Synonyms	7-(Difluoromethyl)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid; 7-(Difluoromethyl)-6-pyrazolo[1,5-a]pyrimidinecarboxylic Acid; 1160246-20-7; 7-Difluoromethyl-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid; Pyrazolo[1,5-a]pyrimidine-6-carboxylic acid, 7-(difluoromethyl)-; 7-(Difluoromethyl)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 1160246-20-7)
EINECS	Contact for details

Quality Control

Every batch of 7-(Difluoromethyl)Pyrazolo[1,5-A]Pyrimidine-6-Carboxylic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.